The new twhirl looks great. Twhirl is a client that lets you track a bunch of different services like Twitter, identi.ca, FriendFeed and Seemic. The new version lets you record to Seemsic, search Twitters (in a very smart way) and post via Ping.fm. For me (I'm biased), the Ping.fm integration is key. Now I can do my posting and reading from Twhirl. The service is in a closed test period, but I think it will be released very soon.
My status update streams are still a bit of a mess with comments all over the place, but this is a step in the right direction to try to help make it easier to keep track of things.